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PEA safeguards towards bacterial an infection by way of innate immune modulation involving MCs, macrophages and microglia. Prophylactic PEA in a dose of 0.one mg/kg overall body excess weight extended survival fee and diminished neuro-inflammation within an aged murine bacterial meningitis model, while in the absence of antibiotics [42].The exogeno
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These Tables record key protein targets and ligands in this post which might be hyperlinked to corresponding entries in , the popular portal for facts within the IUPHAR/BPS Manual to PHARMACOLOGY (Southan et al.,All 3 experiments are in keeping with current literature on PEA’s considerable therapeutic index, that makes it an interesting prospect
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